Nucleosides and Nucleotides

MEDESSE Labs’s dynamic team has vast experience in sugar/base modifications, phosphonates synthesis, and scaffold synthesis. We deliver quality products at a reliable time and competitive cost.

Our Capability

• Modification of base
  • - A, U, G, C modifications
  • - Metal mediated modification (Suzuki, Stille, Heck, Negishi, Sonogashira, and Buchwald Amination)
  • - C2, C6, C8 of Base modification
  • - Fluorination
• Modification of Sugar
  • - Deoxy spirocyclic Nucleosides
  • - Fluorination
  • - Methylation
  • - Alkylation
• Synthesis of Nucleoside Scaffold / Building Blocks
• Library Synthesis of Nucleoside Derivatives
• Acyclic Nucleosides
• Bicyclic and Tricyclic Nucleosides
• Nucleoside Phosphate Esters
• Scale-ups in multi-gram quantities